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Advanced Research in Sclerosis Dog drying rapidly to deliver aAbout This Hardback An autoimmune disorder in which the connective tissue of the body gets affected is known as systemic sclerosis or systemic scleroderma. It is classified into two forms non systemic and systemic. The systemic condition can be limited or diffuse. Limited scleroderma is characterized by Raynaud's phenomenon, sclerodactyly, telangiectasia, esophageal dysfunction and calcinosis. Diffuse scleroderma, in contrast, can cause pulmonary,